About NCTN Biospecimen Banks

The NCTN Biospecimen Banks (NCTN Banks) constitute a large collection of well-annotated biospecimens from patients enrolled in controlled treatment trials with definitive endpoints. The scope and quality of the NCTN Banks’ annotated specimens provide a unique resource for clinical and basic investigators worldwide from both academia and industry to answer well designed, hypothesis driven correlative science questions.

Biospecimen resources are fundamental to the scientific mission of the NCI NCTN Program, the aim of which is to conduct definitive clinical studies that advance cancer care. A majority of the current NCI-supported large phase I/II, II, and III clinical trials include a correlative science component and/or a plan for biospecimen banking.

Investments in translational research initiatives by the NCTN Groups and Banks help to design the next generation of cancer clinical trials using knowledge gained from correlative science studies conducted using NCTN Banks’ biospecimens.

Access to eligible NCTN Banks biospecimens requires an application, which can be submitted by any investigator, regardless of their connection to or participation in the NCTN Groups. Scientific merit reviews are performed for all applications by the NCTN Core Correlative Sciences Committee (NCTN-CCSC). Please see additional details about the NCTN Banks Biospecimen Access process.